Salt screening is a crucial step in modern drug development, as the presence of various salt forms can increase the dissolution rate and oral bioavailability of an API. By identifying and assessing various salt forms of a drug substance, drug developers are able to select an optimal counterion early in the lifecycle and reduce the chance of risk later in drug development.
Salt screening also enables drug developers to modify the physical properties of an API while preserving the benefits of a crystalline solid form.
- Effective development of drug candidates
- Improved bioavailability
- Enhanced physiochemical properties