Harnessing the power of pharmaceutical salts and cocrystals is a promising approach to improving low aqueous solubility during drug development.
In our webinar entitled ‘A Novel Series of Ivosidenib-Polymer Cocrystals’, Veranova’s Associate Principal Scientist, Adam Patterson, explores polymer cocrystallization, an innovative method that uses polymers instead of traditional small molecule coformers to enhance solubility and stability. This approach offers a unique opportunity to align drug substance and formulation development workflows.
Watch the webinar to learn:
- How polymer cocrystals can improve solubility in non-ionizable compounds
- When and why to consider this approach, especially for isostructural solvates
- Insights from an Ivosidenib case study, including single crystal structures and scale-up
- Practical considerations for applying this in real-world development
