Recent advances in ADC linker technology have enhanced ADC stability in the bloodstream, reduced payload hydrophobicity, and enabled higher DAR and multiple payload constructs. A consequence of these advancements is significantly increased complexity of the linker and linker-payload structures and associated synthetic chemistry challenges.
In this webinar, hosted by Hanson Wade, Veranova’s Global Vice President of Chemical Development Operations, Dr William Sanders, highlights the structural features of the newest classes of linkers and addresses some of the challenges in the synthesis and purification of payload-linker constructs for the preparation of clinical ADCs so you can understand how best to utilize these advances in your ADC constructs.
