Customized Solutions with an Integrated Approach

At Veranova, our extensive experience in specialized and complex API development enables the delivery of customized solutions across a wide range of specialty modalities. Spanning research and development to commercial-scale GMP production, our capabilities cover four key areas:

  • Drug Conjugates & Linkers
  • Polyethylene Glycols (PEGs) & Lipids
  • Proteolysis Targeting Chimeras (PROTACs)
  • Nucleotides, Oligonucleotides and Peptides (TIDES).

Veranova’s strength lies in an integrated approach which incorporates our expertise in chemical process development, all-scale manufacturing, and process optimization. Dedicated to achieving optimal results for our customers, we provide access to state-of-the-art process and analytical development labs, isolator suites for manufacture of highly potent compounds, lab to commercial scale chromatography, and full analytical support.

ADC molecule

Drug Conjugates & Linkers

Our experience with multiple linker systems and diverse types of polymers, including PEGs, polyesters, polyamides, polysaccharides, and polypeptides, means that we can support you all the way from early development through to commercial GMP manufacturing.

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PEGs & Lipids

Our PEGs & Lipids capabilities focus on enhancing drug solubility, physical properties, and supporting formulation strategies that may influence pharmacokinetics. Veranova has extensive experience in the custom synthesis of PEG and lipid drug linkers and modifiers. Leveraging our expertise in solid state science and particle engineering, we offer comprehensive optimization, including unique paths to develop ionic cocrystals and improve drug purity and solubility.

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Abstract image of a PEG molecule

PROTACs

In the PROTACs space, Veranova has the infrastructure and experience to address the challenges of complex chemistry, potent compound handling, properties that may influence bioavailability, and crystallization with confidence. Veranova offers solutions to produce specific warhead stereoisomers. We improve bioavailability through salt and cocrystal screening, amorphous solid dispersions, and particle engineering strategies. Our crystallization workflows are designed to optimize the isolation, stability, and scalability of PROTAC candidates and intermediates.

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TIDES

Veranova offers end-to-end support for custom nucleosides and activated monomers, oligonucleotides, peptides, and drug modifiers. Veranova can synthesize complex molecules utilizing liquid phase, solid phase, and/or fragment approach. Our purification and finishing capabilities extend to all-scale chromatography, thin film evaporation, spray drying, and crystallization. With over 10 years of experience, Veranova is a trusted partner for high-quality, cost-effective TIDES development and manufacturing.

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TIDES molecule

Partner with Us

At Veranova, we provide industry-leading specialized R&D, analytical development, and manufacturing solutions for complex molecules. Our commitment to innovation positions us at the forefront of complex drug development as we continue to expand our portfolio and explore emerging therapeutic modalities.

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Resources

Abstract image of ADC molecules

Analytical Techniques for Antibody-Drug Conjugates (ADCs): Comprehensive Insights

TIDES molecule

Rising TIDES: The Growth of Peptide and Oligonucleotide Therapeutics

The ABC of ADCs: Fundamentals of Technical, Regulatory, and Clinical Insights

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Discover new ways to advance your science with Veranova.

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