Our highly skilled process chemists and analytical scientists possess over a decade of experience developing and scaling up processes for linking small molecule payloads to polymers in support of antibody drug conjugates (ADCs), polymer drug conjugates and other drug delivery applications.
- Expertise from development through large scale cGMP manufacturing
- High potency compounds
- SafeBridge® category 4
- Controlled Substances I-V
- Control of molecular weight distribution
- Diafiltration/tangential flow filtration (TFF) /reverse osmosis
- Large column chromatography
- Analytical method development and validation
- GPC/SEC for MW determination
- MALS coupled with Viscostarfor MW and hydrodynamic radius determination
- Lyophilization
